Modern Synthetic Methods for the Stereoselective Construction of 1,3-Dienes

The 1,3-butadiene motif is widely found in many natural products and drug candidates with relevant biological activities. Moreover, dienes are important targets for synthetic chemists, due to their ability give access a wide range of functional group transformations, including broad C-C bond-forming processes. Therefore, the stereoselective preparation have attracted much attention over past decades, search new protocols continues unabated. aim this review an overview diverse methodologies that emerged last decade, focus on processes meet requirements efficiency sustainability modern organic chemistry.